Maureen Su Lab

Understanding What Causes Autoimmune Disease

Read About our Research

Welcome to the Maureen Su Lab

Our group is broadly interested in in understanding what causes autoimmune disease in order to develop targeted therapies for these conditions. Using insight gained from studying autoimmune disease, we are also interested in developing therapies that enhance anti-cancer immunity. Funded by the NIH U19 grant, we host the only Autoimmunity Center of Excellence on the West Coast. Our close proximity to the UCLA Hospitals and Clinics allows ample opportunities for translational research. UCLA Health is ranked #1 in California and #4 in the nation by US News and World Report.

New Autoimmunity Center of Excellence at UCLA

Learn about UCLA's new Autoimmunity Center of Excellence, led by Dr. Maureen Su!

Read the UCLA Newsroom Article

Publications Highlight

Read Dr. Su's editorial in the New England Journal of Medicine on JAK Inhibition Immunotherapy for APS-1.
Read PhD graduate Dr. Mandy Cheng's article in Nature Immunology on UTX-regulated NK cell-intrinsic sex differences.

Autoimmunity

We are interested in understanding age-associated and genetic factors of autoimmune diseases using both mouse models and patient samples. Our work is highly translational and aims to have direct relevance to human disease, determining the efficacy of biological inhibitors.

Cancer

Our recent studies have shown that epigenetic regulation by UTX plays an important role in T cell-mediated autoimmunity. We are interested in extending this knowledge to epigenetic regulation of the innate and adaptive immune system in the context of anti-cancer immunity.

Sex Differences

Ongoing work in our lab seeks to understand the biological factors underlying sexual dimorphism in autoimmunity and anti-cancer immunity. We are interested in the contributions of hormones, chromosome complement, and expression of the long non-coding RNA Xist.